Non-linear patterns in age-related DNA methylation may reflect CD4(+) T cell differentiation

DNA methylation (DNAm) is an important epigenetic process involved in the regulation of gene expression. While many studies have identified thousands of loci associated with age, few have differentiated between linear and non-linear DNAm trends with age. Non-linear trends could indicate early- or la...

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Publicat a:Epigenetics
Autors principals: Johnson, Nicholas D., Wiener, Howard W., Smith, Alicia K., Nishitani, Shota, Absher, Devin M., Arnett, Donna K., Aslibekyan, Stella, Conneely, Karen N.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501198/
https://ncbi.nlm.nih.gov/pubmed/28387568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1314419
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