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Non-linear patterns in age-related DNA methylation may reflect CD4(+) T cell differentiation

DNA methylation (DNAm) is an important epigenetic process involved in the regulation of gene expression. While many studies have identified thousands of loci associated with age, few have differentiated between linear and non-linear DNAm trends with age. Non-linear trends could indicate early- or la...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Johnson, Nicholas D., Wiener, Howard W., Smith, Alicia K., Nishitani, Shota, Absher, Devin M., Arnett, Donna K., Aslibekyan, Stella, Conneely, Karen N.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501198/
https://ncbi.nlm.nih.gov/pubmed/28387568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1314419
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