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Origins, recruitment, and regulation of CD11c(+) cells in inflamed islets of autoimmune diabetes mice

CD11c(+) cells increase greatly with islet inflammation in non-obese diabetic mice and contribute to autoimmune destruction of pancreatic beta cells. In this study, we investigated their origin and mechanism of recruitment. CD11c(+) cells in inflamed islets resembled classical dendritic cells (DC) b...

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Foilsithe in:J Immunol
Main Authors: Klementowicz, Joanna E., Mahne, Ashley E., Spence, Allyson, Nguyen, Vinh, Satpathy, Ansuman T., Murphy, Kenneth M., Tang, Qizhi
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501182/
https://ncbi.nlm.nih.gov/pubmed/28550204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601062
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