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Amplification of Autoimmune Response through Induction of Dendritic Cell Maturation in Inflamed Tissues

Dendritic cells (DCs) are essential in T cell-mediated destruction of insulin-producing β cells in the islets of Langerhans in type 1 diabetes. In this study, we investigated T cell induction of intra-islet DC maturation during the progression of the disease in both autoimmune-prone NOD and resistan...

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Autors principals: Melli, Kristin, Friedman, Rachel S., Martin, Ashley E., Finger, Erik B., Miao, Gang, Szot, Gregory L., Krummel, Matthew F., Tang, Qizhi
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057894/
https://ncbi.nlm.nih.gov/pubmed/19234153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803543
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