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The role of fluorinated alcohols as mobile phase modifiers for LC-MS analysis of oligonucleotides

Hexafluoroisopropanol (HFIP) has been widely used as an acidic modifier for mobile phases for liquid chromatography-mass spectrometry (LC-MS) analysis of oligonucleotides ever since the first report of its use for this purpose. This is not surprising considering the exceptional performance of HFIP c...

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Détails bibliographiques
Publié dans:J Am Soc Mass Spectrom
Auteurs principaux: Basiri, Babak, van Hattum, Hilde, van Dongen, William D., Murph, Mandi M., Bartlett, Michael G.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500909/
https://ncbi.nlm.nih.gov/pubmed/27644940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-016-1500-3
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