Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease

To date, there is no effective Alzheimer's disease (AD)-modifying therapy. Nonetheless, combination therapy holds promise, and nutraceuticals (natural dietary compounds with therapeutic properties) and their synthetic derivatives are well-tolerated candidates. We tested whether combination ther...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Mori, Takashi, Koyama, Naoki, Tan, Jun, Segawa, Tatsuya, Maeda, Masahiro, Town, Terrence
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
Soggetti:
Neurobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500797/
https://ncbi.nlm.nih.gov/pubmed/28512130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.762658
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