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Altered ECM Deposition by Diabetic Foot Ulcer-Derived Fibroblasts Implicates Fibronectin in Chronic Wound Repair

Current chronic wound treatments often fail to promote healing of diabetic foot ulcers (DFU), leading to amputation and increased patient morbidity. A critical mediator of proper wound healing is the production, assembly, and remodeling of the extracellular matrix (ECM) by fibroblasts. However, litt...

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Bibliografiske detaljer
Udgivet i:Wound Repair Regen
Main Authors: Maione, Anna G., Smith, Avi, Kashpur, Olga, Yanez, Vanessa, Knight, Elana, Mooney, David J., Veves, Aristidis, Tomic-Canic, Marjana, Garlick, Jonathan A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500637/
https://ncbi.nlm.nih.gov/pubmed/27102877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/wrr.12437
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