Genome-wide DNA methylation analysis identifies a metabolic memory profile in patient-derived diabetic foot ulcer fibroblasts

Diabetic foot ulcers (DFUs) are a serious complication of diabetes. Previous exposure to hyperglycemic conditions accelerates a decline in cellular function through metabolic memory despite normalization of glycemic control. Persistent, hyperglycemia-induced epigenetic patterns are considered a cent...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Epigenetics
Hlavní autoři: Park, Lara K, Maione, Anna G, Smith, Avi, Gerami-Naini, Behzad, Iyer, Lakshmanan K, Mooney, David J, Veves, Aristidis, Garlick, Jonathan A
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622843/
https://ncbi.nlm.nih.gov/pubmed/25437049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15592294.2014.967584
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky