Antiglioma effects of cytarabine on leptomeningeal metastasis of high-grade glioma by targeting the PI3K/Akt/mTOR pathway

Leptomeningeal metastasis (LM) of high-grade glioma is a highly lethal disease requiring new effective therapeutic measures. For both de novo or relapsed glioma with LM, intrathecal cytarabine chemotherapy is not frequently used for first-line and relapse protocols. We encountered a clinical case de...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhao, Kai-Hong, Zhang, Can, Bai, Yue, Li, Yan, Kang, Xun, Chen, Jian-Xin, Yao, Kun, Jiang, Tao, Zhong, Xiao-Song, Li, Wen-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500519/
https://ncbi.nlm.nih.gov/pubmed/28721010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S135711
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