Dexmedetomidine Protects Against Glucocorticoid Induced Progenitor Cell Apoptosis in Neonatal Mouse Cerebellum

OBJECTIVES: Glucocorticoids (GC) are used to improve respiratory mechanics in preterm infants despite clinical evidence linking neonatal GC therapy to cerebellar pathology. In developing mouse cerebellum, the GC dexamethasone (DEX) causes rapid GC-induced neural progenitor cell apoptosis (GINA). Foc...

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Detalhes bibliográficos
Publicado no:J Matern Fetal Neonatal Med
Main Authors: O’Connor, Shawn David, Cabrera, Omar Hoseá, Dougherty, Joseph D., Singh, Sukrit, Swiney, Brant Stephen, Salinas-Contreras, Patricia, Farber, Nuri Bradford, Noguchi, Kevin Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500416/
https://ncbi.nlm.nih.gov/pubmed/27677376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14767058.2016.1241763
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