Overexpression of Uridine-Cytidine Kinase 2 Correlates with Breast Cancer Progression and Poor Prognosis

PURPOSE: Uridine-cytidine kinase (UCK) 2 is a rate-limiting enzyme involved in the salvage pathway of pyrimidine-nucleotide biosynthesis. Recent studies have shown that UCK2 is overexpressed in many types of cancer and may play a crucial role in activating antitumor prodrugs in human cancer cells. I...

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Publicado en:J Breast Cancer
Autores principales: Shen, Guosong, He, Pingya, Mao, Yingying, Li, Peipei, Luh, Frank, Ding, Guohui, Liu, Xiyong, Yen, Yun
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Breast Cancer Society 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500396/
https://ncbi.nlm.nih.gov/pubmed/28690649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4048/jbc.2017.20.2.132
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