A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer

Menopausal estrogen-alone therapy (ET) is a well-established risk factor for serous and endometrioid ovarian cancer. Genetics also plays a role in ovarian cancer, which is partly attributable to 18 confirmed ovarian cancer susceptibility loci identified by genome-wide association studies. The interp...

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Vydáno v:Int J Cancer
Hlavní autoři: Lee, Alice W., Bomkamp, Ashley, Bandera, Elisa V., Jensen, Allan, Ramus, Susan J., Goodman, Marc T., Rossing, Mary Anne, Modugno, Francesmary, Moysich, Kirsten B., Chang-Claude, Jenny, Rudolph, Anja, Gentry-Maharaj, Aleksandra, Terry, Kathryn L., Gayther, Simon A., Cramer, Daniel W., Doherty, Jennifer A., Schildkraut, Joellen M., Kjaer, Susanne K., Ness, Roberta B., Menon, Usha, Berchuck, Andrew, Mukherjee, Bhramar, Roman, Lynda, Pharoah, Paul D., Chenevix-Trench, Georgia, Olson, Sara, Hogdall, Estrid, Wu, Anna H., Pike, Malcolm C., Stram, Daniel O., Pearce, Celeste Leigh
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500237/
https://ncbi.nlm.nih.gov/pubmed/27420401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30274
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