Identification of dipeptidyl peptidase 3 as the Angiotensin-(1–7) degrading peptidase in human HK-2 renal epithelial cells

Angiotensin-(1–7) (Ang-(1–7)) is expressed within the kidney and exhibits renoprotective actions that antagonize the inflammatory, fibrotic and pro-oxidant effects of the Ang II-AT1 receptor axis. We previously identified a peptidase activity from sheep brain, proximal tubules and human HK-2 proxima...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Peptides
Главные авторы: Cruz-Diaz, Nildris, Wilson, Bryan A., Pirro, Nancy T., Brosnihan, K. Bridget, Marshall, Allyson C., Chappell, Mark C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500233/
https://ncbi.nlm.nih.gov/pubmed/27315786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2016.06.005
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы