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PLK4 phosphorylation of CP110 is required for efficient centriole assembly

Centrioles are assembled during S phase and segregated into 2 daughter cells at the end of mitosis. The initiation of centriole assembly is regulated by polo-like kinase 4 (PLK4), the major serine/threonine kinase in centrioles. Despite its importance in centriole duplication, only a few substrates...

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Bibliografske podrobnosti
izdano v:Cell Cycle
Main Authors: Lee, Miseon, Seo, Mi Young, Chang, Jaerak, Hwang, Deog Su, Rhee, Kunsoo
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499911/
https://ncbi.nlm.nih.gov/pubmed/28562169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1325555
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