An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly

Polo-like kinase 4 (Plk4) initiates an early step in centriole assembly by phosphorylating Ana2/STIL, a structural component of the procentriole. Here, we show that Plk4 binding to the central coiled-coil (CC) of Ana2 is a conserved event involving Polo-box 3 and a previously unidentified putative C...

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Detaylı Bibliyografya
Yayımlandı:J Cell Biol
Asıl Yazarlar: McLamarrah, Tiffany A., Buster, Daniel W., Galletta, Brian J., Boese, Cody J., Ryniawec, John M., Hollingsworth, Natalie Ann, Byrnes, Amy E., Brownlee, Christopher W., Slep, Kevin C., Rusan, Nasser M., Rogers, Gregory C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Rockefeller University Press 2018
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881488/
https://ncbi.nlm.nih.gov/pubmed/29496738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201605106
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