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Perturbation of DROSHA and DICER expression by Human Papillomavirus 16 Oncoproteins

Many tumors, including cervical carcinoma, show dysregulated expression of the microRNA processing machinery, specifically DROSHA and DICER. Some cervical cancers exhibit chromosome 5p amplifications and DROSHA is the most significantly upregulated transcript and is observed in all tumors with 5p ga...

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Bibliographic Details
Published in:Virology
Main Authors: Harden, Mallory, Munger, Karl
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499708/
https://ncbi.nlm.nih.gov/pubmed/28448850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.04.022
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