DNA synthesis determines the binding mode of the human mitochondrial single-stranded DNA-binding protein

Single-stranded DNA-binding proteins (SSBs) play a key role in genome maintenance, binding and organizing single-stranded DNA (ssDNA) intermediates. Multimeric SSBs, such as the human mitochondrial SSB (HmtSSB), present multiple sites to interact with ssDNA, which has been shown in vitro to enable t...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Morin, José A., Cerrón, Fernando, Jarillo, Javier, Beltran-Heredia, Elena, Ciesielski, Grzegorz L., Arias-Gonzalez, J. Ricardo, Kaguni, Laurie S., Cao, Francisco J., Ibarra, Borja
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499585/
https://ncbi.nlm.nih.gov/pubmed/28486639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx395
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