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Modulation of cyclobutane thymine photodimer formation in T(11)-tracts in rotationally phased nucleosome core particles and DNA minicircles
Cyclobutane pyrimidine dimers (CPDs) are DNA photoproducts linked to skin cancer, whose mutagenicity depends in part on their frequency of formation and deamination. Nucleosomes modulate CPD formation, favoring outside facing sites and disfavoring inward facing sites. A similar pattern of CPD format...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499554/ https://ncbi.nlm.nih.gov/pubmed/28525579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx427 |
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