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Poly(A)-ClickSeq: click-chemistry for next-generation 3΄-end sequencing without RNA enrichment or fragmentation

The recent emergence of alternative polyadenylation (APA) as an engine driving transcriptomic diversity has stimulated the development of sequencing methodologies designed to assess genome-wide polyadenylation events. The goal of these approaches is to enrich, partition, capture and ultimately seque...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Routh, Andrew, Ji, Ping, Jaworski, Elizabeth, Xia, Zheng, Li, Wei, Wagner, Eric J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499544/
https://ncbi.nlm.nih.gov/pubmed/28449108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx286
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