Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer

Stromal content heavily impacts the transcriptional classification of colorectal cancer (CRC), with clinical and biological implications. Lineage-dependent stromal transcriptional components could therefore dominate over more subtle expression traits inherent to cancer cells. Since in patient-derive...

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Udgivet i:Nat Commun
Main Authors: Isella, Claudio, Brundu, Francesco, Bellomo, Sara E., Galimi, Francesco, Zanella, Eugenia, Porporato, Roberta, Petti, Consalvo, Fiori, Alessandro, Orzan, Francesca, Senetta, Rebecca, Boccaccio, Carla, Ficarra, Elisa, Marchionni, Luigi, Trusolino, Livio, Medico, Enzo, Bertotti, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499209/
https://ncbi.nlm.nih.gov/pubmed/28561063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15107
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