Male Infertility Is Responsible for Nearly Half of the Extinction Observed in the Mouse Collaborative Cross

The goal of the Collaborative Cross (CC) project was to generate and distribute over 1000 independent mouse recombinant inbred strains derived from eight inbred founders. With inbreeding nearly complete, we estimated the extinction rate among CC lines at a remarkable 95%, which is substantially high...

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Vydáno v:Genetics
Hlavní autoři: Shorter, John R., Odet, Fanny, Aylor, David L., Pan, Wenqi, Kao, Chia-Yu, Fu, Chen-Ping, Morgan, Andrew P., Greenstein, Seth, Bell, Timothy A., Stevans, Alicia M., Feathers, Ryan W., Patel, Sunny, Cates, Sarah E., Shaw, Ginger D., Miller, Darla R., Chesler, Elissa J., McMillian, Leonard, O’Brien, Deborah A., de Villena, Fernando Pardo-Manuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2017
Témata:
Multiparental Populations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499172/
https://ncbi.nlm.nih.gov/pubmed/28592496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.199596
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