Male Infertility Is Responsible for Nearly Half of the Extinction Observed in the Mouse Collaborative Cross

The goal of the Collaborative Cross (CC) project was to generate and distribute over 1000 independent mouse recombinant inbred strains derived from eight inbred founders. With inbreeding nearly complete, we estimated the extinction rate among CC lines at a remarkable 95%, which is substantially high...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Shorter, John R., Odet, Fanny, Aylor, David L., Pan, Wenqi, Kao, Chia-Yu, Fu, Chen-Ping, Morgan, Andrew P., Greenstein, Seth, Bell, Timothy A., Stevans, Alicia M., Feathers, Ryan W., Patel, Sunny, Cates, Sarah E., Shaw, Ginger D., Miller, Darla R., Chesler, Elissa J., McMillian, Leonard, O’Brien, Deborah A., de Villena, Fernando Pardo-Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Multiparental Populations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499172/
https://ncbi.nlm.nih.gov/pubmed/28592496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.199596
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