Hunter syndrome: isolation of an iduronate-2-sulfatase cDNA clone and analysis of patient DNA.

Iduronate 2-sulfatase (IDS, EC 3.1.6.13) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. We have isolated and...

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Bibliografski detalji
Glavni autori: Wilson, P J, Morris, C P, Anson, D S, Occhiodoro, T, Bielicki, J, Clements, P R, Hopwood, J J
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC54990/
https://ncbi.nlm.nih.gov/pubmed/2122463
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