Antitumoral Cascade-Targeting Ligand for IL-6 Receptor-Mediated Gene Delivery to Glioma

The effective treatment of glioma is largely hindered by the poor transfer of drug delivery systems across the blood-brain barrier (BBB) and the difficulty in distinguishing healthy and tumorous cells. In this work, for the first time, an interleukin-6 receptor binding I(6)P(7) peptide was exploited...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther
Hauptverfasser: Wang, Shanshan, Reinhard, Sören, Li, Chengyi, Qian, Min, Jiang, Huiling, Du, Yilin, Lächelt, Ulrich, Lu, Weiyue, Wagner, Ernst, Huang, Rongqin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498832/
https://ncbi.nlm.nih.gov/pubmed/28502470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.04.023
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