Aptavalve-gated Mesoporous Carbon Nanospheres image Cellular Mucin and provide On-demand Targeted Drug Delivery

In this report, we present a mesoporous carbon nanosphere that can target drugs to tumors and image tumor biomarkers. A single-strand DNA (P(0) aptamer) aptavalve was capped on the surface of doxorubicin-loaded oxide mesoporous carbon nanospheres (Dox-OMCN-P(0)) through π-π stacking for real-time im...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Li, Chengyi, Qian, Min, Wang, Shanshan, Jiang, Huilin, Du, Yilin, Wang, Jianxin, Lu, Weiyue, Murthy, Niren, Huang, Rongqin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595134/
https://ncbi.nlm.nih.gov/pubmed/28900512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.18692
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