Aging is protective against pressure overload cardiomyopathy via adaptive extracellular matrix remodeling

When challenged by hemodynamic stress, aging hearts respond differently to young hearts. Preclinical models of heart disease should take into account the effects of age. However, in the transverse aortic constriction (TAC) model of pressure-overload cardiomyopathy, the larger aorta of aging mice has...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Am J Cardiovasc Dis
Main Authors: Geng, Xiaoyong, Hwang, Joy, Ye, Jianqin, Shih, Henry, Coulter, Brianna, Naudin, Crystal, Jun, Kristine, Sievers, Richard, Yeghiazarians, Yerem, Lee, Randall J, Boyle, Andrew J
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2017
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498818/
https://ncbi.nlm.nih.gov/pubmed/28695053
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