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Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP
The multi-domain transcriptional coactivators CBP/p300 integrate a multitude of signaling inputs, interacting with more than 400 proteins via one or more of their globular domains. While CBP/p300 function is typically considered in terms of these structured domains, about half of the protein consist...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5498717/ https://ncbi.nlm.nih.gov/pubmed/28680062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04611-x |
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