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Mesenchymal Stem Cell-Derived Factors Restore Function to Human Frataxin-Deficient Cells

Friedreich’s ataxia is an inherited neurological disorder characterised by mitochondrial dysfunction and increased susceptibility to oxidative stress. At present, no therapy has been shown to reduce disease progression. Strategies being trialled to treat Friedreich’s ataxia include drugs that improv...

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Bibliografiske detaljer
Udgivet i:Cerebellum
Main Authors: Kemp, Kevin, Dey, Rimi, Cook, Amelia, Scolding, Neil, Wilkins, Alastair
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498643/
https://ncbi.nlm.nih.gov/pubmed/28456899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12311-017-0860-y
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