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Mesenchymal Stem Cell-Derived Factors Restore Function to Human Frataxin-Deficient Cells

Friedreich’s ataxia is an inherited neurological disorder characterised by mitochondrial dysfunction and increased susceptibility to oxidative stress. At present, no therapy has been shown to reduce disease progression. Strategies being trialled to treat Friedreich’s ataxia include drugs that improv...

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Detalhes bibliográficos
Publicado no:Cerebellum
Main Authors: Kemp, Kevin, Dey, Rimi, Cook, Amelia, Scolding, Neil, Wilkins, Alastair
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498643/
https://ncbi.nlm.nih.gov/pubmed/28456899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12311-017-0860-y
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