PfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum

Calcium Dependent Protein Kinases are key effectors of calcium signaling in malaria parasite. PfCDPK1 is critical for asexual development of Plasmodium falciparum, but its precise function and substrates remain largely unknown. Using a conditional knockdown strategy, we here establish that this kina...

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Pubblicato in:Nat Commun
Autori principali: Kumar, Sudhir, Kumar, Manish, Ekka, Roseleen, Dvorin, Jeffrey D., Paul, Aditya S., Madugundu, Anil K., Gilberger, Tim, Gowda, Harsha, Duraisingh, Manoj T., Keshava Prasad, T. S., Sharma, Pushkar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498596/
https://ncbi.nlm.nih.gov/pubmed/28680058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00053-1
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