PfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum

Calcium Dependent Protein Kinases are key effectors of calcium signaling in malaria parasite. PfCDPK1 is critical for asexual development of Plasmodium falciparum, but its precise function and substrates remain largely unknown. Using a conditional knockdown strategy, we here establish that this kina...

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Vydáno v:Nat Commun
Hlavní autoři: Kumar, Sudhir, Kumar, Manish, Ekka, Roseleen, Dvorin, Jeffrey D., Paul, Aditya S., Madugundu, Anil K., Gilberger, Tim, Gowda, Harsha, Duraisingh, Manoj T., Keshava Prasad, T. S., Sharma, Pushkar
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498596/
https://ncbi.nlm.nih.gov/pubmed/28680058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00053-1
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