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Virtual Screening, pharmacophore development and structure based similarity search to identify inhibitors against IdeR, a transcription factor of Mycobacterium tuberculosis

ideR, an essential gene of Mycobacterium tuberculosis, is an attractive drug target as its conditional knockout displayed attenuated growth phenotype in vitro and in vivo. To the best of our knowledge, no inhibitors of IdeR are identified. We carried out virtual screening of NCI database against the...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Rohilla, Akshay, Khare, Garima, Tyagi, Anil K.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498548/
https://ncbi.nlm.nih.gov/pubmed/28680150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04748-9
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