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Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated differentiation.

Expression of the cloned human nerve growth factor receptor (NGFR) cDNA in cell lines can generate both high- and low-affinity binding sites. Since the inability to respond appropriately to differentiation factors such as NGF may contribute to determining the malignant phenotype of neuroblastomas, w...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Pleasure, S J, Reddy, U R, Venkatakrishnan, G, Roy, A K, Chen, J, Ross, A H, Trojanowski, J Q, Pleasure, D E, Lee, V M
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1990
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54983/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2172988/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.21.8496
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