Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated differentiation.

Expression of the cloned human nerve growth factor receptor (NGFR) cDNA in cell lines can generate both high- and low-affinity binding sites. Since the inability to respond appropriately to differentiation factors such as NGF may contribute to determining the malignant phenotype of neuroblastomas, w...

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Detalhes bibliográficos
Main Authors: Pleasure, S J, Reddy, U R, Venkatakrishnan, G, Roy, A K, Chen, J, Ross, A H, Trojanowski, J Q, Pleasure, D E, Lee, V M
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC54983/
https://ncbi.nlm.nih.gov/pubmed/2172988
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