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EFFECTS OF CELL CYCLE NOISE ON EXCITABLE GENE CIRCUITS

We assess the impact of cell cycle noise on gene circuit dynamics. For bistable genetic switches and excitable circuits, we find that transitions between metastable states most likely occur just after cell division and that this concentration effect intensifies in the presence of transcriptional del...

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Bibliografiske detaljer
Udgivet i:Phys Biol
Main Authors: VELIZ-CUBA, ALAN, GUPTA, CHINMAYA, BENNETT, MATTHEW R., JOSIĆ, KREŠIMIR, OTT, WILLIAM
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498228/
https://ncbi.nlm.nih.gov/pubmed/27902489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/13/6/066007
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