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Transcriptional delay stabilizes bistable gene networks

Transcriptional delay can significantly impact the dynamics of gene networks. Here we examine how such delay affects bistable systems. We investigate several stochastic models of bistable gene networks and find that increasing delay dramatically increases the mean residence times near stable states....

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Detalhes bibliográficos
Main Authors: Gupta, Chinmaya, López, José Manuel, Ott, William, Josić, Krešimir, Bennett, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941076/
https://ncbi.nlm.nih.gov/pubmed/23952450
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