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Crystallographic structure of truncated CCL21 and putative sulfotyrosine-binding site
CCL21 chemokine binds the G protein-coupled receptor CCR7, aiding not only in immune response but also in cancer metastasis. Compared with other chemokines, CCL21 has a unique extended unstructured C-terminus that is truncated in some naturally occurring variants. We have solved the X-ray crystallog...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5498006/ https://ncbi.nlm.nih.gov/pubmed/27617343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00304 |
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