Identification of V122I (Val122Ile) transthyretin cardiac amyloidosis (ATTR) using serum retinol-binding protein 4 (RBP4) and a clinical prediction model

IMPORTANCE: Transthyretin amyloid cardiomyopathy (ATTR) is an under-recognized cause of heart failure (HF) in the elderly, owing in part to difficulty in diagnosis. ATTR can result from mutant TTR protein with one of the most common mutations in the United States, V122I, present in 3.43% of African...

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Pubblicato in:JAMA Cardiol
Autori principali: Arvanitis, Marios, Koch, Clarissa M, Chan, Gloria G., Arancivia, Celia M.T., LaValley, Michael, Jacobson, Daniel, Berk, John L., Connors, Lawreen H., Ruberg, Frederick L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497744/
https://ncbi.nlm.nih.gov/pubmed/28196196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2016.5864
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