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Fluorouracil enhances photodynamic therapy of squamous cell carcinoma via a p53 -independent mechanism that increases protoporphyrin IX levels and tumor cell death
Photodynamic therapy (PDT), using 5-aminolevulinic acid (ALA) to drive synthesis of protoporphryin IX (PpIX) is a promising, scar-free alternative to surgery for skin cancers, including squamous cell carcinoma (SCC) and SCC precursors called actinic keratoses (AK). In the United States, PDT is only...
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| Gepubliceerd in: | Mol Cancer Ther |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5497500/ https://ncbi.nlm.nih.gov/pubmed/28336806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0608 |
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