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AMINOGLYCOSIDE RESISTANCE OF PSEUDOMONAS AERUGINOSA IN CYSTIC FIBROSIS RESULTS FROM CONVERGENT EVOLUTION IN THE MEXZ GENE
RATIONALE: Aminoglycoside (AG) resistance by Pseudomonas aeruginosa in Cystic Fibrosis is associated with poorer clinical outcomes and is usually due to overexpression of the efflux pump MexXY. MexXY is regulated by mexZ, one of the most commonly mutated genes in CF P. aeruginosa isolates. Little is...
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| Publicado no: | Thorax |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5497499/ https://ncbi.nlm.nih.gov/pubmed/27325751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2015-208027 |
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