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Immune regulation and viral diversity as correlates of natural and treatment induced immune control in persistent hepatitis B virus (HBV) infection

In long-lasting chronic hepatitis B, the phenomenon of cytotoxic CD8 T lymphocytes (CTL) exhaustion and unresponsiveness to HBV-specific stimuli was shown to be crucial for the loss of immune control of the virus and disease activity. There is evidence that Tregs, Th17 cells and Bregs seem to be imp...

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Publicat a:Clin Exp Hepatol
Autors principals: Parfieniuk-Kowerda, Anna, Jaroszewicz, Jerzy, Flisiak, Robert
Format: Artigo
Idioma:Inglês
Publicat: Termedia Publishing House 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497408/
https://ncbi.nlm.nih.gov/pubmed/28856253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/ceh.2015.51805
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