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Immune regulation and viral diversity as correlates of natural and treatment induced immune control in persistent hepatitis B virus (HBV) infection

In long-lasting chronic hepatitis B, the phenomenon of cytotoxic CD8 T lymphocytes (CTL) exhaustion and unresponsiveness to HBV-specific stimuli was shown to be crucial for the loss of immune control of the virus and disease activity. There is evidence that Tregs, Th17 cells and Bregs seem to be imp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Exp Hepatol
Hauptverfasser: Parfieniuk-Kowerda, Anna, Jaroszewicz, Jerzy, Flisiak, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Termedia Publishing House 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497408/
https://ncbi.nlm.nih.gov/pubmed/28856253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/ceh.2015.51805
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