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RASSF4 controls SOCE and ER–PM junctions through regulation of PI(4,5)P(2)

RAS association domain family 4 (RASSF4) is involved in tumorigenesis and regulation of the Hippo pathway. In this study, we identify new functional roles of RASSF4. First, we discovered that RASSF4 regulates store-operated Ca(2+) entry (SOCE), a fundamental Ca(2+) signaling mechanism, by affecting...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Autores principales: Chen, Yu-Ju, Chang, Chi-Lun, Lee, Wan-Ru, Liou, Jen
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496610/
https://ncbi.nlm.nih.gov/pubmed/28600435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201606047
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