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Phosphatidylinositol 4,5-Bisphosphate Homeostasis Regulated by Nir2 and Nir3 Proteins at Endoplasmic Reticulum-Plasma Membrane Junctions

Phosphatidylinositol (PI) 4,5-bisphosphate (PIP(2)) at the plasma membrane (PM) constitutively controls many cellular functions, and its hydrolysis via receptor stimulation governs cell signaling. The PI transfer protein Nir2 is essential for replenishing PM PIP(2) following receptor-induced hydroly...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chang, Chi-Lun, Liou, Jen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505499/
https://ncbi.nlm.nih.gov/pubmed/25887399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.621375
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