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Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin

Soluble cytosolic proteins vital to axonal and presynaptic function are synthesized in the neuronal soma and conveyed via slow axonal transport. Our previous studies suggest that the overall slow transport of synapsin is mediated by dynamic assembly/disassembly of cargo complexes followed by short-r...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Ganguly, Archan, Han, Xuemei, Das, Utpal, Wang, Lina, Loi, Jonathan, Sun, Jichao, Gitler, Daniel, Caillol, Ghislaine, Leterrier, Christophe, Yates, John R., Roy, Subhojit
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496608/
https://ncbi.nlm.nih.gov/pubmed/28559423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201604028
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