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MDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer
The two murine double minute (MDM) family members MDM2 and MDMX are at the center of an intense clinical assessment as molecular target for the management of cancer. Indeed, the two proteins act as regulators of P53, a well-known key controller of the cell cycle regulation and cell proliferation tha...
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| Published in: | J Hematol Oncol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5496368/ https://ncbi.nlm.nih.gov/pubmed/28673313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0500-5 |
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