Drosophila CP190- and dCTCF-mediated enhancer blocking is augmented by SUMOylation

BACKGROUND: Chromatin insulators shield promoters and chromatin domains from neighboring enhancers or chromatin regions with opposing activities. Insulator-binding proteins and their cofactors mediate the boundary function. In general, covalent modification of proteins by the small ubiquitin-like mo...

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Vydáno v:Epigenetics Chromatin
Hlavní autoři: Jox, Theresa, Buxa, Melanie K., Bohla, Dorte, Ullah, Ikram, Mačinković, Igor, Brehm, Alexander, Bartkuhn, Marek, Renkawitz, Rainer
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496309/
https://ncbi.nlm.nih.gov/pubmed/28680483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-017-0140-6
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