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Drosophila CP190- and dCTCF-mediated enhancer blocking is augmented by SUMOylation
Abstract Background Chromatin insulators shield promoters and chromatin domains from neighboring enhancers or chromatin regions with opposing activities. Insulator-binding proteins and their cofactors mediate the boundary function. In general, covalent modification of proteins by the small ubiquitin...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2017-07-01
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| Colecção: | Epigenetics & Chromatin |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13072-017-0140-6 |
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