Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1(−/−) mice

The ERCC1-XPF heterodimer is a structure-specific endonuclease involved in both nucleotide excision repair and interstrand crosslink repair. Mice carrying a genetic defect in Ercc1 display symptoms suggestive of a progressive, segmental progeria, indicating that disruption of one or both of these DN...

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Bibliografiset tiedot
Päätekijät: Prasher, Joanna M, Lalai, Astrid S, Heijmans-Antonissen, Claudia, Ploemacher, Robert E, Hoeijmakers, Jan H J, Touw, Ivo P, Niedernhofer, Laura J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2005
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC549615/
https://ncbi.nlm.nih.gov/pubmed/15692571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600542
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