CYP2J2 metabolites, epoxyeicosatrienoic acids, attenuate Ang II-induced cardiac fibrotic response by targeting Gα(12/13)

The arachidonic acid-cytochrome P450 2J2-epoxyeicosatrienoic acid (AA-CYP2J2-EET) metabolic pathway has been identified to be protective in the cardiovascular system. This study explored the effects of the AA-CYP2J2-EET metabolic pathway on cardiac fibrosis from the perspective of cardiac fibroblast...

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Veröffentlicht in:J Lipid Res
Hauptverfasser: He, Zuowen, Yang, Yong, Wen, Zheng, Chen, Chen, Xu, Xizhen, Zhu, Yanfang, Wang, Yan, Wang, Dao Wen
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496032/
https://ncbi.nlm.nih.gov/pubmed/28554983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M074229
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