Dalcetrapib and anacetrapib differently impact HDL structure and function in rabbits and monkeys

Inhibition of cholesteryl ester transfer protein (CETP) increases HDL cholesterol (HDL-C) levels. However, the circulating CETP level varies and the impact of its inhibition in species with high CETP levels on HDL structure and function remains poorly characterized. This study investigated the effec...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Lipid Res
Auteurs principaux: Brodeur, Mathieu R., Rhainds, David, Charpentier, Daniel, Mihalache-Avram, Teodora, Mecteau, Mélanie, Brand, Geneviève, Chaput, Evelyne, Perez, Anne, Niesor, Eric J., Rhéaume, Eric, Maugeais, Cyrille, Tardif, Jean-Claude
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2017
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496027/
https://ncbi.nlm.nih.gov/pubmed/28515138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M068940
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